Answer: Creatine ethyl ester malate (CrEEM) is a commercially available synthetic form of creatine that is used in dietary supplements. Structurally, it is creatine with an ethyl group attached and manufacturers using this form report that it provides several advantages over creatine monohydrate (CrM). However, there is no research to support the claim that CrEEM is superior to creatine monohydrate. In fact, the addition of the ethyl group to creatine reduces creatine stability and accelerates its breakdown to creatinine. This reaction substantially reduces creatine availability. So, not only is CrEEM not superior to CrM, but it is quite inferior. And finally, there are more than 500 clinical trials that support the use of CrM and none on CrEEM.